Molina-Montes E, Van Hoogstraten L, Gomez-Rubio P, et al. - Researchers deeply investigated pancreatic cancer (PC) risk according to lifespan smoking patterns and other smoking characteristics within a large European case-control study. Participants were cases (n = 2,009) and controls (n = 1,532) recruited in the PanGenEU study. For participants, tobacco smoking habits, as well as other relevant information, was collected. An increased PC risk was observed among current smokers, those inhaling into the throat, chest, or using non-filtered cigarettes, vs never-smokers. The highest risk of PC was reported among current black tobacco smokers, followed by blond tobacco smokers. Increased PC risk was evident in relation to childhood exposure to tobacco smoke vs parental smoking. Experts found that dose-response links for smoking duration, intensity, cumulative dose, and smoking cessation were non-linear and displayed distinct shapes by tobacco type. Likely effect modification by a family history of PC and diabetes was also observed. Overall, findings showed variations in PC risk by tobacco type and other habit features, as well as revealed non-linear risk links.