Van Hedger K, et al. - The effects of intranasal oxytocin (OT) on cigarette craving, behavioral economic demand for cigarettes, and cigarette consumption, in regular smokers after 18 hours of abstinence, were examined. Some indices of smoking desire and consumption were noted to decrease with the administration of OT, providing modest support for the idea that OT might be effective for reducing cigarette smoking. Findings thereby support the literature suggesting this neuropeptide, which is mainly known for its role in social bonding and attachment, to affect mood and motivational states relevant to addiction.