Auger N, et al. - In order to find out the long-term risk of morbidity and mortality in patients with takotsubo syndrome, a matched cohort study of 174 individuals with takotsubo syndrome was conducted between 1989 and 2006 in Quebec, Canada, with 15 years of follow-up on future hospitalization outcomes. Researchers matched takotsubo individuals to 2 comparison groups, involving 1,736 individuals with acute myocardial infarction and 1,740 population controls. The hazard ratios (HR) and 95% confidence intervals (CI) were calculated for the association of takotsubo syndrome with subsequent in-hospital mortality, cardiovascular morbidity, and other hospitalization outcomes. After 15 years, takotsubo syndrome is correlated with a risk of mortality similar to that of myocardial infarction, but a lower risk of cardiovascular rehospitalization. It was found that individuals with takotsubo syndrome nonetheless have more in-hospital mortality and cardiovascular morbidity compared with population controls.