Aprato A, Sordo L, Costantino A, et al. - The present study was conducted to describe the outcomes of AM at twenty years follow-up through timing/rate of conversion to total knee replacement (TKR) and Knee injury and Osteoarthritis Outcome Score, focusing on detection of specific predictor variables for these outcomes, in patients aged between 50-70 years old. Researchers conducted a retrospective study including a total of 289 patients aged at the surgery between 50 and 70 years old with a diagnosis of degenerative meniscal tear who underwent arthroscopic meniscectomy. A 15.7% conversion rate was recorded at 20 years from AMP to TKR and a mean time between surgeries of seven years. This study’s findings revealed that the subsequent TKR in the 20 years following AM for DMT was significantly correlated with preoperative osteoarthritis and chondral lesion (KL 2; Outerbridge > 2), lateral meniscectomy, age at surgery, female gender, and malalignment. At 20 years follow-up, age superior to 60 years, lateral meniscectomy, and concurrent ACL reconstruction was negative predictors for poor clinical outcomes. Thus, whether individuals present negative predictor factors, the AM should not be proposed as secon- line treatment, continuing with nonoperative management until TKR is unavoidable.