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Outcomes and prognostic factors for aggressive posterior retinopathy of prematurity following initial treatment with intravitreal ranibizumab

BMC Ophthalmology Jun 29, 2018

Tong Q, et al. - Experts identified the factors related to retinal detachment and retreatment of aggressive posterior retinopathy of prematurity (APROP) initially treated with intravitreal ranibizumab (IVR) injection as well as the efficacy of IVR treatment. Findings suggested an effectiveness of IVR injection as a treatment for APROP. They identified the risk factors for retinal detachment in APROP to be older postmenstrual age and low neutrophil count. Moreover, a significant association of retinal hemorrhage and low birth weight (BW) with recurrence and retreatment in non-retinal detachment APROP was noted. Therefore, reexamination of patients with a lower BW, older postmenstrual age, low neutrophil count and retinal hemorrhage should be done in a timely and more frequent manner.
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