Kuzo N, Stähli BE, Erhart L, et al. - Given that coexistence of coronary artery disease and severe aortic stenosis (AS) is a frequent finding, researchers herein determined the effect of normal coronary arteries as a negative risk marker in patients receiving transcatheter aortic valve implantation (TAVI). Based on the presence or absence of normal coronary arteries, severe AS patients receiving TAVI were dichotomized. One-year mortality was assessed as the primary endpoint. While the normal coronary artery and the coronary atherosclerosis groups exhibited similar mortality at 30 days, it was found to be lower in patients with normal coronary arteries at 1 year. Multivariable analysis revealed that 1-year mortality was independently predicted by the presence of normal coronary arteries on coronary angiogram. Overall, in patients with severe AS receiving TAVI, normal coronary arteries was defined as a negative risk marker.