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Outcome by gender in patients with long QT syndrome with an implantable cardioverter defibrillator

Journal of the American Heart Association Oct 16, 2020

Younis A, Aktas MK, Rosero S, et al. - Among patients with long QT syndrome with an implantable cardioverter defibrillator (ICD), this inquiry was performed to assess the incidence of time‐dependent life‐threatening events in both genders. This analysis involved 60 patients with long QT syndrome who had received an ICD for primary or secondary prevention indications. From the date of ICD implant, life‐threatening events were assessed, including ICD shocks for ventricular tachycardia, ventricular fibrillation, or mortality. Females and males were observed for a mean duration of 14±6 years and 12±6 years, respectively, after ICD implantation. Irrespective of ICD indications or genotype, no significant difference in the risk and rate of life‐threatening events was found between male patients and female patients with long QT syndrome with an ICD. Experts noted that ventricular tachycardia/ventricular fibrillation was not terminated by first shock in a substantial proportion of cases with long QT syndrome.

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