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Optimal timing of complete revascularization in patients with ST-segment elevation myocardial infarction and multivessel disease: A pairwise and network meta-analysis

Clinical Epidemiology Sep 01, 2018

Guo WQ, et al. - This meta-analysis was conducted to assess the ideal revascularization strategy for treating patients with ST-segment elevation myocardial infarction and multivessel disease. They searched PubMed, the Cochrane Library, clinicaltrial.gov, and the reference lists of relevant papers covering the period between the year 2000 and March 20, 2017. Findings revealed that, compared with culprit only revascularization (COR), early complete revascularization (CR) was related to significantly lowered risks of major adverse cardiac events (MACE), myocardial infarction (MI), and repeat revascularization, but not of all-cause mortality. It was noted that early CR had the highest probability of being the first treatment option during MACE (89.2%), myocardial infarction (MI) (83.3%), and repeat revascularization (80.4%). Researchers found that the optimal timing of CR is still questionable considering the small number of relevant studies.

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