Fiorentino TV, et al. - Using MEDLINE, a literature search was performed to examine the implication of 1-hour postload glucose concentration (1-h-PG) determination in prediction of type 2 diabetes mellitus (T2DM) and cardiovascular disease. Although 1-h-PG determination is not currently recommended by the American Diabetes Association for identifying high-risk individuals, findings show that a value of 1-h-PG ≥155 mg/dL may be a helpful tool to distinguish those who are at increased risk of T2DM and cardiovascular disease vs those with normal glucose tolerance.