One‐year mortality after intensification of outpatient diuretic therapy
Journal of the American Heart Association Jul 26, 2020
Madelaire C, Gustafsson F, Stevenson LW, et al. - Researchers investigated the impact of outpatient intensification of diuretic therapy on the risk of mortality in patients with heart failure (HF). All Danish patients who received a diagnosis of HF from 2001 to 2016 and were treated with angiotensin‐converting enzyme inhibitor/angiotensin receptor blocker and β blocker within 120 days were identified using nationwide administrative registers. This study sample included 74,990 patients, with a median age of 71 years. Experts reported almost 2‐fold risk of death during the next year in correlation with outpatient intensification events in patients with HF. Although a higher risk was observed in relation to HF hospitalization, the requirement to intensify diuretics in the outpatient setting is a sign to review as well as intensify attempts to better HF results.
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