Mochache V, Richardson BA, Masese LN, et al. - In view of studies reporting on HIV-infected, antiretroviral therapy (ART)-naïve people who show minimal disease progression despite prolonged infection, researchers sought to determine the characteristics of these long-term non-progressors (LTNPs) in populations mainly infected with non-subtype B HIV-1. Immunologic disease progression was studied in female sex workers in Mombasa, Kenya who acquired HIV-1. An ART-naïve duration of infection ≥ 7 years and a majority of CD4+ cell counts ≥ 600 cells/µl with a non-declining CD4+ trend defined long-term non-progression. Among 332 women who acquired HIV-1 between February 1993 and March 2014, 77 (23%) had ≥ 7 years of follow-up and 13 (17%) were categorized as LTNPs. Age > 30 years at infection and nulliparity were the identified factors linked with long-term non-progression. This indicates a possible influence of age and parity on the likelihood of long-term non-progression. The mechanisms seemed not involving the effects of these variables on viral load.