Pereira CR, de Almeida JVFC, de Oliveira IRC, et al. - Researchers performed this systematic review with the aim to determine occupational brucellosis. Further, they sought the main infection risks for each group exposed to the pathogen. CABI, Cochrane, Pubmed, Scielo, Science Direct, Scopus and Web of Science were searched resulting in 6,123 studies. Of these studies, they selected 63 using the quality assessment tools guided from National Institutes of Health (NIH) and Case Report Guidelines (CARE). They considered great exposure to disease in five different job-related groups: rural workers, abattoir workers, veterinarians and veterinary assistants, laboratory workers and hunters. The analysis of the articles revealed following as the main risk factors and exposure sources involved in the occupational infection: direct contact with animal fluids, failure to comply with the use of personal protective equipment, accidental exposure to live attenuated anti-brucellosis vaccines and non-compliance with biosafety standards. From job-related infection, the following Brucella species were frequently isolated: Brucella melitensis, Brucella abortus, Brucella suis and Brucella canis. Furthermore, a meta-analysis was conducted using the case-control studies and established that animal breeders, laboratory workers and abattoir workers are at 3.47 times higher risk of becoming infected with Brucella spp. than others individuals that have no contact with the possible sources of infection.