Traven S, Synovec J, Walton ZJ, et al. - The present study was conducted to assess the current disparities for major lower extremity amputation in patients with critical limb ischemia (CLI) and infection. Researchers performed a retrospective analysis of the National Surgical Quality Improvement Program's database for the years 2011 to 2017. They applied multivariate models to isolate the impact of race and ethnicity on the likelihood of a below-knee or above-knee amputation (BKA and AKA, respectively) for CLI secondary to type 2 diabetes mellitus, atherosclerosis, peripheral vascular disease, chronic osteomyelitis, and deep soft-tissue infections. The data revealed that notable racial and ethnic disparities for lower extremity amputations persist, with a higher proportion of black and Hispanic patients undergoing amputation in comparison with limb salvage procedures for atraumatic CLI and infection in this nationally representative, cohort-based study.