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New severity grading system for Fuchs endothelial corneal dystrophy using anterior segment optical coherence tomography

Acta Ophthalmologica Dec 04, 2020

Yasukura Y, Oie Y, Kawasaki R, et al. - In this observational case series involving 75 eyes of 43 patients with Fuchs endothelial corneal dystrophy (FECD) and 33 eyes of 33 healthy individuals, researchers reported a new severity grading system for FECD using anterior segment optical coherence tomography (AS‐OCT). In order to determine the AS‐OCT‐based grading scores, pachymetry and posterior elevation maps were used. Thirty‐three eyes were graded by the modified Krachmer grade as 0, four as 1, thirteen as 2, fourteen as 3, twenty‐nine as 4, eleven as 5 and four as 6. New severity grading was formulated using only objective assessment and quantitatively shown corneal thickening, predominant flattening of the posterior corneal surface relative to the anterior surface and displacement of the thinnest point away from the central cornea with FECD progression.

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