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New-onset atrial fibrillation predicting for complicating cardiac adverse outcome in scrub typhus infection

Clinical Cardiology Oct 10, 2019

Jang SY, Kang KW, Kim JH, et al. - Researchers utilized data from the National Health Information Database to determine if there exists a significant link between new-onset atrial fibrillation (AF) and 3-month mortality and adverse cardiac complications in scrub typhus infection. Participants were 233,473 patients diagnosed with scrub typhus infection. The probability of having underlying cardiovascular disease was more in individuals with new-onset AF vs those without new-onset AF. A higher incidence risk of concurrent acute heart failure (AHF) (4.1-fold) and ischemic heart disease (IHD) (1.9-fold) was observed in those with new-onset AF vs those without new-onset AF, after being adjusted for demographic factors and comorbidities. Findings revealed a significant association of new-onset AF with 3-month mortality and concurrent AHF and IHD. Hence, a possible role of new-onset AF as a poor prognostic factor for 3-month mortality and cardiac complications in scrub typhus infection was suggested.
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