Djirackor L, et al. - Authors gauged the expression of nestin in primary (PUM) and metastatic uveal melanoma (MUM) samples, and they correlated the findings with histological, clinical and survival data. Findings suggested that in PUM, increased nestin expression was a predictor of a tumour phenotype related to metastatic progression and reduced survival time at the onset of metastasis. A higher percentage of nestin-positive tumour cells in MUM, combined with poor prognostic markers in the PUM led to a shorter survival time after the development of metastases.