Lu PJ, Yankey D, Fredua B, et al. - This study draws on data from the 2018 National Immunization Survey–Teen (NIS–Teen) to evaluate settings of receiving human papillomavirus (HPV) vaccination among adolescents in order to understand what strategies are needed to improve vaccination uptake. Doctor's offices were the most common medical setting in which adolescents aged 13–17 years were vaccinated against HPV. In nonmedical settings, less than 1% of adolescents were immunized. To improve HPV vaccination coverage among adolescents, more work with medical and nonmedical settings is needed to identify and implement appropriate strategies.