Meta-analysis comparing outcomes in patients with and without cardiac injury and coronavirus disease 2019 (COVID 19)
The American Journal of Cardiology Nov 20, 2020
Bansal A, Kumar A, Patel D, et al. - To examine the link between cardiac injury and results in patients suffering from COVID-19, researchers undertook this comprehensive meta-analysis of studies in COVID-19 patients. They focused on the link between cardiac injury and all-cause death, intensive care unit (ICU) admission, mechanical ventilation, acute respiratory distress syndrome (ARDS), acute kidney injury (AKI) and coagulopathy. Also, experts analyzed studies comparing cardiac biomarker levels in survivors vs non-survivors. The final analysis involved 14 studies (3175 patients). In non-survivors vs survivors with COVID-19 infection, significantly elevated concentrations of hs-cTnI, myoglobin, NT-pro BNP and CK-MB were detected. Findings of this meta-analysis revealed that higher mortality, ICU admission, mechanical ventilation and coagulopathy were observed in relation to cardiac injury in patients suffering from COVID-19. However, cardiac injury was not related to raised risk of ARDS or AKI.
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