Maternal-fetal transmission and adverse perinatal outcomes in pregnant women infected with Zika virus: Prospective cohort study in French Guiana
BMJ Nov 04, 2018
Pomar L, et al. - Researchers approximated the rates of maternal-fetal transmission of Zika virus, adverse fetal/neonatal outcomes, and ensuing rates of asymptomatic/symptomatic congenital Zika virus infections up to the first week of life. They included women at any stage of pregnancy with laboratory-confirmed symptomatic or asymptomatic Zika virus infection during the epidemic period in western French Guiana. Results demonstrated congenital infections in about a quarter of fetuses in cases of a known maternal Zika virus infection; out these infected fetuses, a third will have severe complications at birth or suffer fetal loss. They noted the probability that the burden of congenital Zika syndrome is lower than first characterized in South America; this burden may not differ from that of other congenital infections.
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