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Longitudinal change of FEV1 and inspiratory capacity: Clinical implication and relevance to exacerbation risk in patients with COPD

International Journal of COPD Feb 11, 2019

Jo YS, et al. - Researchers analyzed the association of dyspnea severity, quality of life status, and lung function with lung function measurements and exacerbation risk in 982 patients enrolled in the Korea COPD Subgroup Registry and Subtype Research study, to compare the efficacy of FEV1, inspiratory capacity (IC), and IC to total lung capacity (TLC) ratio in the evaluation of COPD and their association with exacerbation. The FEV1, IC, and IC to TLC ratio were noted to display comparable negative correlations with dyspnea severity and quality of life status, and positive correlation with exercise capacity. Findings suggest no significant correlation of longitudinal changes in IC and FEV1 with exacerbation risk.
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