Romoli M, et al. - After a first transient global amnesia (TGA), known as a benign syndrome, in two independent prospective cohorts (OXVASC [Oxford Vascular Study], population-based; NU [Northern Umbria] cohort, TGA registry), researchers determined the long-term risk of stroke. Study participants included 525 patients (mean age was 65.1 [9.5] years) with TGA (425 NU and 100 OXVASC). The most frequent cardiovascular risk factors were hypertension, dyslipidemia, and smoking. With a pooled annual risk of 0.6% and a 5-year cumulative risk of 2.7%, data revealed that the risk of stroke was similar in the two cohorts. When cardiovascular risk factors are treated according to primary prevention guidelines, findings suggested no association of TGA with an enhanced danger of stroke.