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Long-term outcomes of high-risk or inoperable patients who underwent transcatheter aortic valve implantation

The American Journal of Cardiology Jul 04, 2019

Ichibori Y, et al. - In this review of consecutive patients (n=114) who had transcatheter aortic valve implantation (TAVI) for severe aortic stenosis and who were of high surgical risk or inoperable, researchers assessed long-term consequences (≥5 years) and transcatheter heart valve (THV) performance after at least 5 years, based on annual follow-up. Participants had a mean age of 82.7 ± 6.4 years, and 37.7% were men. At 1, 3, 5, and 7 years, the respective estimated cumulative survival rates were 88.6%, 72.8%, 58.8%, and 45.3%. A strong link was evident between albumin <3.5 g/dl and increased long-term death, as revealed in multivariate analysis. The performance of THV was confirmed, by longitudinal transthoracic echocardiography, to be durable up to 7 years in most cases; however, follow-up revealed structural valve degeneration (SVD) in 6 patients (5.3% of the total cohort). Although SVD was not rare, following TAVI, favorable long-term survival and stable THV performance were evident in this study.

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