Wienbergen H, et al. - Researchers performed this RAID-HF (Registry Analysis of Iron Deficiency-Heart Failure) follow-up study to determine the long-term (1-year) impacts of iron deficiency (ID) in heart failure patients with or without anemia. Study participants were consecutive patients with ID and heart failure with reduced ejection fraction (HFrEF) in 11 heart centers in Germany and Switzerland. Findings from RAID-HF showed that long-term mortality and quality of life in patients with HFrEF was affected by ID. Patients with ID had a higher long-term mortality and reported a lower quality of life vs those without ID. In the adjusted analysis ID was a significant predictor of 1-year mortality in patients without anemia. Data also reported an underuse of iron supplementation in current clinical practice. They also observed that to detect patients at higher mortality risk, it is clinically relevant to look for ID diagnosis, especially in patients without anemia.