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Long-term anatomical and functional outcomes after autokeratoplasty

British Journal of Ophthalmology Aug 26, 2020

Sanjuán P, Julio G, Bolaños J, et al. - Via retrospectively performing Kaplan-Meier survival analyses, researchers sought to assess the anatomical and functional outcomes of autologous contralateral penetrating keratoplasty (autokeratoplasty). During a mean follow-up of 11.3 years (from 13 months to 48 years), 31 eyes of 31 patients (19 men), with a mean age of 52 ± 18 years (range 15–81 years) were analyzed. All the recipient eyes showed a transparent cornea at 12 months postoperatively, but 23% displayed functional failure, defined as the final best-corrected visual acuity (BCVA) < 20/400. Sixteen recipient eyes (52%) exhibited anatomical and functional success at the final follow-up. Autokeratoplasty may be a good long-term alternative in patients with one eye having a clear cornea but with irreversible visual dysfunction and the contralateral eye having favourable visual potential limited only by a completely opacified cornea. The most important risk factor for long-term decompensation of the cornea and visual functional failure in the sample was the progression of previous glaucoma.

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