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Local conduction velocity in the presence of late gadolinium enhancement and myocardial wall thinning: A cardiac magnetic resonance study in a swine model of healed left ventricular infarction

Circulation: Arrhythmia and Electrophysiology Apr 26, 2019

Jang J, et al. - In a swine model of healed left ventricular infarction, researchers looked for the link between local conduction velocity (CV) vs late gadolinium enhancement (LGE) and myocardial wall thickness. Cardiovascular magnetic resonance imaging and electroanatomic mapping were performed in six swine with healed myocardial infarction. Using identical protocols, electroanatomic mapping was performed in two healthy controls (one treated with amiodarone and one unmedicated), to establish the baseline CV. They used a triangulation technique to estimate CV. In the presence of LGE, myocardial wall thinning, high LGE heterogeneity, and a high wall thickness gradient, they detected slower CV. For the estimation of CV, a valuable imaging surrogate could be cardiovascular magnetic resonance.
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