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Life expectancy of adult survivors of childhood cancer over 3 decades

JAMA Jan 12, 2020

Yeh JM, Ward ZA, Chaudhry A, et al. - Researchers developed a microsimulation model of competing for mortality risks by utilizing data from the Childhood Cancer Survivor Study on 5-year survivors of childhood cancer diagnosed between 1970 and 1999, in order to project long-term survival and evaluate whether life expectancy will improve among adult survivors of childhood cancer who were treated in more recent decades. Conditional life expectancy was 48.5 years, for 5-year survivors diagnosed in 1970-1979, 53.7 years for those diagnosed in 1980-1989, and 57.1 years for those diagnosed in 1990-1999 were noted in participants of the hypothetical cohort of 5-year survivors of infancy cancer representative of the Childhood Cancer Survivor Study. It was found that evolving treatment methods were projected to be correlated with improved life expectancy following treatment for pediatric cancer, in particular between those who got chemotherapy alone for their childhood cancer diagnosis. In spite of improvements, survivors remain at risk for lower lifespans, particularly when radiotherapy was introduced as part of their childhood cancer treatment.
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