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Left ventricular systolic ejection time is an independent predictor of all‐cause mortality in heart failure with reduced ejection fraction

European Journal of Heart Failure Nov 12, 2020

Alhakak AS, Sengeløv M, Jørgensen PG, et al. - Researchers investigated if outcome in patients with heart failure with reduced ejection fraction (HFrEF) could be predicted by cardiac time intervals obtained by the tissue Doppler imaging (TDI) M‐mode method. This study involved 997 patients with HFrEF (mean age 67 ± 11 years, 74% men). The participants received an echocardiographic assessment including TDI. Experts noted that death risk rose by 9% per 10 ms reduction in systolic ejection time (SET). The link continued to be significant even following multivariable adjustment for clinical as well as echocardiographic parameters. Findings revealed that independent as well as incremental prognostic information about all‐cause mortality was afforded by SET in patients with HFrEF.

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