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Left ventricular systolic ejection time is an independent predictor of all‐cause mortality in heart failure with reduced ejection fraction

European Journal of Heart Failure Nov 25, 2020

Alhakak AS, Sengeløv M, Jørgensen PG, et al. - Given that colour tissue Doppler imaging (TDI) M‐mode through the mitral leaflet represents an easy as well as an accurate method to collect cardiac time intervals including isovolumic contraction time, isovolumic relaxation time and systolic ejection time (SET), researchers investigated if outcome in patients with heart failure with reduced ejection fraction (HFrEF) can be predicted using cardiac time intervals obtained by the TDI M‐mode method. In this study, 997 patients with HFrEF were involved. Participants were assessed via an echocardiographic examination including TDI. Per 10 ms reduction in SET, the risk of death rose by 9%. The link continued to be significant, even following multivariable adjustment for clinical as well as echocardiographic parameters. Overall, experts inferred that independent as well as incremental prognostic information about all‐cause mortality is afforded by SET in patients with HFrEF.

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