Wallerstein A, Gauvin M, Mimouni M, et al. - In this pilot study, researchers sought to evaluate the potential application of corneal higher-order aberration (HOA) excimer ablation map imaging in identifying reproducible keratoconus (KC) features and to investigate whether newly derived map metrics correlate with Pentacam KC indices. There were 12 consecutive eyes of 10 patients diagnosed with KC grade 2 and above that matched the criteria for inclusion. The corneal HOA ablation map showed a recurring, distinct, easily recognizable pattern in KC eyes. The depth of novel HOA ablation map metrics and validated Pentacam KC indices were closely correlated. Novel information can be derived from the corneal HOA ablation map, giving it the ability to diagnose and grade KC as a new modality.