Imbornoni LM, Wise RE, Taravella MJ, et al. - In this investigation involving 31 patients (56 eyes), aged 4-24 years (mean, 12.4), researchers sought to assess patients with Down syndrome for keratoconus and corneal abnormalities utilizing Scheimpflug imaging (Pentacam HR) in a pediatric setting. The Pentacam scans of patients with Down syndrome seen at Children’s Hospital Colorado Ophthalmology Department have been reviewed retrospectively, and the following data were obtained: keratometry values, pachymetry values, components of the Belin ABCD Grading System, the Belin/Ambrosio enhanced ectasia display D value, and topometric indices, including ISV, IVA, and KI. A high frequency of suspected keratoconus and keratoconus was found in pediatric and young adult patients with Down syndrome. Compared with previously reported controls, the corneas in this population had steeper K values and thinner pachymetry values.