Maddox RA, Person MK, Kennedy JL, et al. - Researchers sought to determine Kawasaki disease (KD)-associated hospitalization rates via analyzing the Kids’ Inpatient Database (KID), the National (Nationwide) Inpatient Sample (NIS), and the IBM MarketScan Commercial (MSC) and MarketScan Medicaid (MSM) databases. In addition, they examined their trends from 2006 to the most recent year of available data. For children < 5 years of age, the KD-associated hospitalization rates for the most recent year were 19.8 (95% CI: 17.2–22.3, KID: 2016), 19.6 (95% CI: 16.8–22.4, NIS: 2017), 19.3 (MSC: 2018), and 18.4 (MSM: 2018) per 100,000. KD-associated hospitalization rates were consistent as per the analyses of these large, national databases and there was no increase over time; however, an increase occurred in the percentage of KD hospitalizations with potential KDSS. In view of reports describing increasing incidence elsewhere and the recent identification of a novel virus-associated syndrome with possible Kawasaki-like features, they suggest continued national surveillance as important to identify changes in disease epidemiology.