Carmel S, et al. - Researchers aimed to assess the causal directions of interaction between depression and decline in will to live (WTL) over 2 years in community-dwelling older adults. WTL was noted to predict depressive symptoms (DS) rather than vice versa, thereby suggesting that decline in WTL contributes and leads to depression at present and in future. Health strategies designed to promote WTL may help forestall depression in older adults. Furthermore, in the treatment of depression, psychotherapeutic interventions targeting WTL might be effective.