Cerpa Manito S, Sánchez Trancón A, Torrado Sierra O, et al. - Researchers conducted this retrospective case series to analyze vault differences produced by an implantable collamer lens (ICL) in fellow eyes, showing similar anterior segment anatomy, implanted with a similar ICL (type, size and power), operated with the same surgical technique and evaluated using the same imaging device, in order to determine an expected range of vault inter-eye differences. They analyzed 109 cases of patients bilaterally implanted with EVO-V4c. Using anterior segment optical coherence tomography, patients were analyzed pre- and postoperatively. According to results, mean vault inter-eye differences between fellow eyes (26.0 ± 122.5 μm) were identical. Vaults measured in fellow eyes can present considerable variations, which may reach 25% of the common vault range. This represents a certain degree of baseline variability in the vault. Clinically, in instances where low or high vaults are predicted, these variations assume particular significance.