Muftuoglu IK, et al. - Experts presented the changes in ganglion cell complex (GCC) comprising retina nerve fiber layer (RNFL), ganglion cell layer (GCL), and inner plexiform layer (IPL) in neovascular age-related macular degeneration (AMD) patients by manually correcting the automated segmentation errors. In neovascular AMD, diffuse thickening of inner retinal layers may overestimate actual GCC thickness within fovea. The likeliness of reflection of more cells or tissue was not suggested by this pseudo-increase in GCC thickness and inner retinal layers in general but rather, suggested diffuse edema which leads to a falsely increased reading of layer thickness. The assessment of other conditions that lead to reduced inner retinal layer thickness such as glaucoma, optic nerve disease, or retinovascular occlusions is much difficult with such false readings.