Inhibition of human cytomegalovirus replication by tricin is associated with depressed CCL2 expression
Antiviral Research Dec 17, 2017
Akai Y, et al. - This research was designed to investigate whether the CCL2-CCR2 axis is involved in the anti-human cytomegalovirus (HCMV) effects of tricin in human embryonic lung fibroblast (HEL) cells. In a dose-dependent manner, CCL2 reversed the tricin-mediated inhibition of HCMV virion production. The authors revealed that through depressing CCL2 expression, tricin appeared to exert anti-HCMV activity.
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