Della Volpe Waizel M, et al. - In patients with cataract formation against those of healthy controls with clear lenses, researchers compared metabolic (oxygen saturation; %) and anatomical parameters (retinal vessel diameter; μm) of retinal vessel oximetry (RO). In total, 62 patients (96 eyes) were examined: 51 eyes from 33 cataract patients were compared with 45 eyes from 29 controls with clear lenses. When compared with healthy controls, cataract eyes exhibited significantly lower A-SO₂ and A-V SO₂ values. Cortical opacities showed significant interactions with the A-SO₂, V-SO₂ and the A-V SO₂ parameters within the cataract group. Such findings indicate that measurements of optical retinal oxygen are influenced by the cataract-induced light scatter. When compared with nuclear opacification, nuclear colour and posterior cataract formation, cortical opacities displayed the highest influence on RO measurement.