Mofors J, et al. - Among patients with primary Sjögren's syndrome (pSS) in Sweden (n=945) and matched controls from the general population (n=9,048), researchers ascertained if infections increase the risk of developing pSS. Using conditional logistic regression models, data were analyzed. According to findings, infections increase the risk of developing pSS, most prominently SSA/SSB autoantibody-positive disease, indicating that microbial immunity triggers could be involved in the pathogenetic process of pSS. There was no significant association between gastrointestinal infections and risk of pSS.