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Individual prognosis at diagnosis in nonmetastatic prostate cancer: Development and external validation of the PREDICT Prostate multivariable model

PLoS Medicine Apr 05, 2019

Thurtle DR, et al. - Authors investigated 10,089 men to establish and validate an individualized prognostic model to study prostate cancer (PCa)-specific mortality (PCSM) vs other causes of mortality and to estimate the influence of treatment on survival. They also noted multiple cases who suffered lifelong side effects from a treatment they might not have needed. They reported a new risk model, named 'PREDICT Prostate,' which predicted survival outcomes with a high degree of accuracy for conservative management and radical treatment, with concordance indices up to 0.84.

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