Fujihara FMF, de Arruda Mello PA, Lindenmeyer RL, et al. - The present study was conducted to evaluate differences in the thickness of the individual macular layers between early, moderate, and severe glaucomatous eyes and compare them with healthy controls. Researchers enrolled individuals with glaucoma presenting typical optic nerve head findings, high intraocular pressure with or without visual field (VF) damage and normal controls. All individuals had undergone 24– 2 perimetry and spectral-domain OCT. Individuals were classified into three groups (early, moderate, and severe) based on the mean deviation of the VF and a healthy control group. For the study, a sum of 109 eyes qualified: 14 in the control group and 52, 18 and 25 in the early, moderate and severe groups, respectively. This study's findings demonstrate that individual macular layer measurement applying the inner and outer circles of the ETDRS grid is beneficial to assess different stages of glaucoma. Future studies are needed to explore the inner nuclear layer thickening and outer nuclear layer thinning in advanced glaucoma.