Nazir S, Ahuja KR, Donato A, et al. - Researchers used the National Readmission Database from January 2012 to September 2015, to determine the incidence, clinical features, as well as results of acute coronary syndrome (ACS) post-transcatheter aortic valve replacement (TAVR). A significantly higher incidence of acute kidney injury, ischemic stroke, vascular complications, cardiogenic shock, cardiac arrest, mechanical circulatory support, and in‐hospital mortality was observed in TAVR patients with ACS vs those without ACS. In addition, longer lengths of stay and hospital charges were reported for TAVR with ACS. History of PCI, hyperlipidemia, chronic blood loss anemia, chronic kidney disease, fluid and electrolyte disorders, and weight loss, were identified as positive predictors of ACS. Findings demonstrated that ACS following TAVR was uncommon but was related to worse clinical results and increased healthcare resource use.