Cairns V, et al. - Through a retrospective descriptive cohort study of 8.4 million people registered with general practitioners with 52.4 million person-years of observation between January 1, 2001, and December 31, 2012, researchers estimated the annual incidence of Lyme disease (LD) in the UK. Over the years 2001 to 2012, the number of cases of LD grew quickly, resulting in an estimated incidence rate of 12.1 per 100,000 people per year; in 2012, there was a total of 7,738 LD cases in the UK. The greatest incidence rates and number of cases were in Scotland, followed by South West and South England, though LD was discovered in every UK region. The number of cases in the UK in 2019 could be over 8,000 if the number of cases kept rising since the end of the study term. In comparison with earlier estimates, the incidence of LD is about threefold higher, and people were at risk across the entire UK. Increased awareness of preventive measures is needed.