Shiels MS, et al. - Given the significance of chronic infection with hepatitis C virus (HCV) and hepatitis B virus (HBV) as causative in hepatocellular carcinoma (HCC), researchers investigated how, among older Americans, viral hepatitis contributes to the recent increasing trends in HCC incidence. HCC cases among individuals aged ≥66 years were identified using data from the Surveillance, Epidemiology, and End Results–Medicare linkage (SEER-Medicare) for the years 2001 through 2013; the HCV and HBV status of these HCC cases were assessed using Medicare files. Findings revealed a rapid increase in HCC rates among Americans aged ≥66 years between 2001 and 2013. The substantial contribution to this increase is related to HCV-attributable cases, but there also appeared to be a rise in the rates of HBV-attributable and HCV/HBV-unrelated HCC during this period.