Park JN, Gaydos CA, White RH, et al. - Researchers investigated cisgender female sex workers (CFSWs) for chlamydia, gonorrhea, and trichomonas infection prevalence, incidence, and predictors. In this prospective observational cohort study, 250 street-based CFSWs were surveyed and tested for sexually transmitted infections at baseline, 3, 6, 9, and 12 months. At baseline, chlamydia, gonorrhea, trichomonas was prevalent in 10.5%, 12.6%, and 48.5%, respectively. Over 1 year of observation, the investigators identified past year sex work initiation as predictive of both chlamydia incidence and gonorrhea incidence. Client sexual violence was identified as predictive of gonorrhea incidence, and having female sexual partners was predictive of trichomonas incidence. An inverse association of having a usual healthcare provider with trichomonas was observed. Despite regular testing, notification, and treatment referral, the infection rates remained elevated through follow-up, indicating the urgent need for focused and multifaceted interventions for sex workers and their sexual partners.