Incidence and predictors of atrial fibrillation episodes as detected by implantable loop recorder in patients at risk (from the LOOP study)
American Heart Journal Oct 29, 2019
Diederichsen SZ, Haugan KJ, Brandes A, et al. - Researchers evaluated atrial fibrillation (AF) through long-term continuous screening and identified the factors that could predict episodes lasting ≥ 6 minutes, ≥ 5.5 hours or ≥ 24 hours, respectively. From the general population, they recruited 597 patients aged ≥ 70 years and diagnosed with ≥ 1 of hypertension, diabetes, previous stroke, or heart failure. These patients received implantable loop recorder with remote monitoring. Individuals with a history of AF or cardiac implantable electronic device were excluded. They identified the presence of AF in 209 (35%) of the patients during 40 [37;42] months of continuous monitoring. Findings showed that long-term monitoring in at-risk patients led to the detection of a considerable burden of previously unknown AF. Factors that were independently related to AF detection were slower resting sinus rate and higher body mass index, NT-proBNP, and troponin T at baseline. An improved prediction of AF episodes ≥ 24 hours was achieved by adding these markers to a model of gender, age, and comorbidities.
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