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Implementation of a standardised and quality-assured enhanced gonococcal antimicrobial surveillance programme in accordance with WHO protocols in Kampala, Uganda

Sexually Transmitted Infections Oct 25, 2020

Kakooza F, Musinguzi P, Workneh M, et al. - In the present study, the researchers sought to evaluate the establishment, design and implementation of a standardised and quality-assured gonococcal surveillance programme and to characterize the susceptibility patterns of the cultured gonococcal isolates in Kampala, Uganda. From March 2018 to September 2019, consecutive males with urethral discharge syndrome were recruited from 10 surveillance sites in Kampala City, Uganda, in collaboration with the Ministry of Health using the WHO Enhanced Gonococcal Antimicrobial Surveillance Programme (EGASP) protocol. Of the 1,013 males selected, 73.1% (740/1013) had a positive Gram stain and 51.1% (n = 518) were culture-positive for NG. The authors established a standardised, quality-assured WHO EGASP. Using Etest, 458 isolates with associated epidemiological surveillance data have been detected over a span of 1.5 years, which by far exceeds the minimum 100 isolates per year and the country requested by the WHO Global GASP to detect AMR levels with confidence. It is possible to use these isolates with epidemiological data to establish population level interventions.

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