Fan J, et al. - Whether tricuspid regurgitation (TR) and right ventricular (RV) dysfunction may have a deleterious effect on outcomes after transcatheter aortic valve replacement (TAVR) was investigated. Researchers identified articles revealing the prognostic impact of TR and RV dysfunction on outcomes after TAVR, from MEDLINE/PubMed, EMBASE, ISI Web of Science, and Cochrane databases via a comprehensive literature search. In accordance with the heterogeneity, they adopted a random or fixed effect model. This analysis included nine studies with a total of 6,466 patients. According to the findings, a worse prognosis after TAVR was observed in association with the presence of both baseline moderate or severe TR and RV dysfunction. Based on these findings, careful evaluation of right heart function by the heart team before the TAVR procedure was recommended for clinical decision making.