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Impact of mitral stenosis on survival in patients undergoing isolated transcatheter aortic valve implantation

American Journal of Cardiology Jan 30, 2019

Sannino A, et al. - In patients undergoing transcatheter aortic valve implantation (TAVI) because of the presence of severe symptomatic aortic stenosis (AS), researchers investigated the prevalence and impact on survival of baseline mitral stenosis (MS) via this retrospective study. Among 928 consecutive patients with severe, symptomatic AS undergoing TAVI in two institutions, patients with baseline mean mitral gradient (MMG)≥10 mmHg, vs those with ≥5 and <10 mmHg and <5 mmHg, had a lower mitral valve area (2.4±0.94 vs 2.1±0.86 vs 1.5±0.44 cm2), a lower prevalence of MR≥2+ (5.9% vs 28.6% and 15.6%), a higher prevalence of severe mitral annular calcium (70.6% vs 45.6% and 13.0%), and a higher systolic pulmonary arterial pressure (50.6±12.1 vs 47.2±14.5 and 41.6±14.4). They observed an uncommon occurrence of severe calcific MS in patients undergoing TAVI, and higher long-term mortality was noted in association with its presence, but not with the presence of moderate MS.

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