Hashimoto Y, et al. - In this historical cohort study involving 19,685 Japanese people [average age and BMI were 45.5 ± 9.5 years old and 22.6 ± 3.3 kg/m²] who received health-checkup programs from 2003 to 2016, researchers illustrated the effect of metabolically healthy obese (MHO) on incident gastric cancer. According to four metabolic factors (hypertension, impaired fasting glucose, hypertriglyceridemia, and low HDL-cholesterol), each subject was classified as metabolically healthy (no metabolic abnormalities) or metabolically abnormal (one or more metabolic abnormalities). In order to identify the individual with obesity, BMI > 25.0 kg/m² was used. The gastric cancer incident rate was 0.65 per 1,000 persons-years over the median follow-up period of 5.5 years. The authors discovered that people with MAO, but not those with MHO, were at increased risk for incident gastric cancer. Therefore, for incident gastric cancer, more focus is required on the presence of metabolic abnormalities rather than obesity itself.