Impact of left ventricular mass/end-diastolic volume ratio by three-dimensional echocardiography on two-dimensional global longitudinal strain and diastolic function in native hypertensive patients
Journal of Hypertension Sep 08, 2019
Lembo M, et al. - Given a link between high left ventricular (LV) mass/end-diastolic volume ratio (LVM/EDV) and LV dysfunction and myocardial fibrosis in hypertensive patients, researchers investigated whether 3D-echo-derived LVM/EDV ratio can help detect early systolic and diastolic dysfunction in relation with LV concentric geometry in native hypertensive patients. They performed 2D-echo, including computation of 2D-derived global longitudinal strain (GLS), and 3D-echo on 144 newly diagnosed, never treated hypertensive patients. Two groups were defined: raised 3D-LVM/EDV (≥ 1.23 in women and ≥ 1.22 in men), corresponding to LV concentric geometry (n = 50), and normal ratio (< 1.23 in women and < 1.22 in men) corresponding to LV normal or eccentric geometry (n = 94). In native hypertensive patients, the detection of an early diastolic and longitudinal systolic dysfunction was enabled by 3D echocardiographic evaluation of LV concentric geometry. Specifically, an independent association of 3D-LVM/EDV ratio with both E/e′ ratio and GLS was found.
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