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Impact of diastolic dysfunction on long‐term mortality and quality of life after transcatheter aortic valve replacement

Catheterization and Cardiovascular Interventions Apr 20, 2020

Anantha‐Narayanan M, Malik U, Mbai M, et al. - To clarify if diastolic dysfunction (DD) influences the prognosis of patients having aortic stenosis undergoing transcatheter aortic valve replacement (TAVR), researchers undertook this investigation. They included 222 patients, mean age 78 (±8) years, undergoing TAVR. The participants underwent evaluation of DD with preoperative echocardiography and NT‐pro BNP. Advanced (Grades II–III) DD was identified to be related to higher pre‐procedural NT‐pro BNP levels, worse quality of life but similar surgical risk. According to the findings, preoperative NT‐pro BNP levels as well as echocardiographic indices of indeterminate or advanced DD were found to be related to increased long‐term mortality post-TAVR but similar improvements in quality of life.

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